If any of the following are present or suspected, please refer the patient to the emergency department (via ambulance if necessary) or follow local emergency care protocols or seek emergent medical advice if in a remote region.
Adult
Stroke/transient ischaemic attack (TIA)
- Patient with acute neurological symptoms of a stroke; multiple/crescendo TIA
- New acute symptoms
Progressive loss of neurological function
- Acute onset severe:
- ataxia
- vertigo
- visual loss
- Acute severe exacerbation of known MS
Seizures/epilepsy
- Status epilepticus/epilepsy with concerning features:
- first seizure
- focal deficit post-ictally
- seizure associated with recent trauma
- persistent severe headache > 1 hour post-ictally
- seizure with fever
Headache/migraine
- Headache with concerning features:
- sudden onset/thunderclap headache
- severe headache with signs of systemic illness (fever, neck stiffness, vomiting, confusion, drowsiness)
- first severe headache age > 50 years
- severe headache associated with recent head trauma
- recent onset headaches in young obese females
- headaches with papilledema
- >50 years with raised CRP/ESR or if giant cell arteritis or vasculitis suspected
Movement disorders
Other referrals to emergency
- Altered level of consciousness
- Bilateral limb weakness with or without bladder and/or bowel dysfunction
- Acute rapidly progressive weakness (Guillain-Barre Syndrome, myelopathy)
- Delirium/sudden onset confusion with or without fever
Paediatric
Seizures/epilepsy
- New onset seizures that require emergency care/advice
- Status epilepticus (convulsive or non-convulsive)
- Developmental/cognitive/psychiatric regression accompanying new onset or ongoing epileptic seizures
- New onset seizure with new neurological deficit (e.g. focal weakness, speech impairment, cognitive impairment) – call 000 for emergency assessment for stroke and transport to the Emergency Department
- Specific seizure types with epileptic encephalopathy risk e.g. infant with possible epileptic spasms
- High initial seizure burden (>5 seizures, before first AED), excluding typical absence seizures
- Neonate / infant (<12-month-old) with epileptic seizure onset
Headaches/migraine
- Headache with papilledema or change in vision/double vision (excluding established migraine with visual aura) or new neurological examination findings (e.g. sixth nerve palsy, gait disturbance, focal weakness)
- Headaches that wake at night or headaches immediately on wakening
- New severe headaches
- Sudden onset headache reaching maximum intensity within 5 minutes (= explosive onset)
- Focal neurological features
- Associated with significant persisting change of personality or cognitive ability or deterioration in school performance
Functional neurological symptoms
- The patient is unable to mobilize safely or has frequent falls/seizure like attacksAddition
Movement disorder
- Abrupt onset or deterioration of a movement disorder
- Acute onset of ataxia / chorea
- Impairment of function i.e. walking, attend school
Hypotonic infant
- Tachypnoea (signs of respiratory distress such as accessory muscle use are NOT seen in patients with neuromuscular disorders)
- Feeding difficulties with weight loss
Gait abnormality, isolated motor delay or focal weakness
- Acute onset of (or rapidly progressive) weakness e.g. Guillain Barre syndrome, transverse myelitis
- Acute onset focal weakness (suspected stroke – call 000)
- Breathing difficulties (NB tachypnoea may be the only sign of respiratory distress in a child with a neuromuscular condition)
- Feeding or swallowing difficulties
- Acute foot drop or acute onset focal neuropathy
Stroke
- Acute stroke – call 000 and request urgent transfer (timelines apply for t-PA and thrombectomy for embolic/thrombotic stroke)
Other neurological conditions
- Developmental/ intellectual impairment or behavioural / psychiatric disorders with regression
- Acute encephalopathy, acute confusional state, altered level of consciousness